Sheffield United boss Chris Wilder says his side "have to wise up quickly" after they were beaten by Southampton in a tight game at Bramall Lane.
The Blades have now won just one of their opening five games on their Premier League return.
Sheffield United manager Chris Wilder speaking to BBC Match of the Day: "I didn't think we deserved anything from the game today. Out of possession it was far too comfortable for them and in possession we weren't brave enough and we turned it over too much.
Manchester United continuing their recent trend of positive result going as this weekend they defeated League One outfit, Sheffield United.
However, that result was not considered pleasing enough for Man United boss Louis Van Gaal, who believes that his side should do much better.
Hull City made their way into the final stage of FA Cup battle this season after winning a thrilling semifinals against Sheffield United.
The League One side made a bright start on that encounter as they went one goal up on 19 minutes from Jose Baxter's effort.
English League One side, Charlton Athletic continue to surprise everyone as they got themselves in the semifinals stage of this seasons' FA Cup after eliminating struggling Championship side, Charlton Athletic this past weekend.
Aston Villa saw their FA Cup run stopped in the third round after suffering a rather disappointing home defeat against League One side, Sheffield United this past weekend. The Villans were actually playing in front of their home crowd, but things didn't seem to go well for them as instead of taking the lead in that weekend encounter, they found themselves trailing after 20 minutes from Jamie Murphy's effort.
Yeovil Town 2-0 Sheffield United highlights: Yeovil Town open their chance in getting a promotion into the Championship Division after they got themselves advanced into the final of League One play off stage by eliminating Sheffield United.
Sheffield United 1-0 Yeovil Town highlights: Sheffield United took an advantage in the first leg of League Two promotion play offs battle after grabbing a slender 1-0 victory over Yeovil Town last Friday.
Oxford United 0-3 Sheffield United highlights: Sheffield United got themselves a passage into the fourth round of FA Cup after picking up a comfortable victory over their opponent, Oxford United last weekend.
Highlights: Dramatic scenes occurred already in the second round of FA Cup when home side Sheffield United made a brilliant late come back to beat their opponent Port Vale and grabbed a ticket into the next round.